Tag Archives: smoking and dna

Smoking Kills Millions Of People Around The World

Not Succeeding is a failure only if you do not try to quit smoking again.

Results from the World Health Organisation (WHO) show that currently there are 1.3 billion smokers in the world.

The same data show that every 8 seconds somewhere in the world one person dies from the consequences of smoking. Smoking is the leading cause of premature deaths in the world.

Experts calculated that the number of deaths caused by smoking will increase by 10 million annually until 2020.

In Croatia, every third person is a smoker, of which 33.8% are men and 21.7% are women.

Smoking is often considered just a habit, but it is actually a much more serious problem.

Smoking is an addiction on three levels – psychological, emotional and physical.

The World Health Organization prepared an International Classification of Diseases which includes smoking addiction as a mental organic disorder.

How Does Nicotine Lead to Addiction?

Smoking ImagesNicotine has psychoactive effects.

It links to nicotine receptors in the brain, and in this way it increases the release of neurotransmitters, especially dopamine which gives a sense of pleasure. That’s why the majority of smokers feels satisfaction when smoking.

What are the Consequences of Smoking?

One of the most fatal results of smoking is lung carcinoma, of which one person dies every 30 seconds.

Around 90% in men and 80% in women of lung cancers are caused by smoking.

Smokers have 22 times greater possibilities of getting lung cancer that non-smokers.

More than 600,000 people die of cardiovascular illnesses that appear as a consequence of smoking every year.  Apart from that, smoking can damage sperm and skew DNA which can cause abortions or congenital deformations of the smokers’ descendants.

Also, sterility happens more often to smokers that non-smokers, because it reduces the number of sperm and the blood flow into the penis.

Making the Decision to Quit Smoking

The benefits of quitting smoking are huge and they are immediately visible. However, those who ask for expert advise have the best opportunity to stop smoking. Those who stop on their own, rarely manage to succeed in their intention, because it is an addiction that hits people emotionally, physically and psychologically.

Not Succeeding is a failure only if you do not try to quit smoking again – doctors say. That is why it is necessary not to give up. Seek support and beat the statistics before it’s to late.

Source: Antonija Zbiljski

Cigarette Ingredients and Composition

Cigarettes look deceptively simple, consisting of paper tubes containing chopped up tobacco leaf, usually with a filter at the mouth end.

In fact, they are highly engineered products, designed to deliver a steady dose of nicotine.

Cigarette tobacco is blended from two main leaf varieties: yellowish ‘bright’, also known as Virginia where it was originally grown, contains 2.5-3% nicotine; and ‘burley’ tobacco which has higher nicotine content (3.5-4%).

US blends also contain up to 10% of imported ‘oriental’ tobacco which is aromatic but relatively low (less than 2%) in nicotine.

In addition to the leaf blend, cigarettes contain ‘fillers’ which are made from the stems and other bits of tobacco, which would otherwise be waste products. These are mixed with water and various flavorings and additives. The ratio of filler varies among brands.

For example, high filler content makes a less dense cigarette with a slightly lower tar delivery. Additives are used to make tobacco products more acceptable to the consumer.

They include humectants (moisturizers) to prolong shelf life; sugars to make the smoke seem milder and easier to inhale; and flavorings such as chocolate and vanilla. While some of these may appear to be quite harmless in their natural form they may be toxic in combination with other substances.

Also when the 600 permitted additives are burned, new products of combustion are formed and these may be toxic.

The nicotine and tar delivery can also be modified by the type of paper used in the cigarette. Using more porous paper will let more air into the cigarette, diluting the smoke and (in theory) reducing the amount of tar and nicotine reaching the smoker’s lungs.

Filters are made of cellulose acetate and trap some of the tar and smoke particles from the inhaled smoke. Filters also cool the smoke slightly, making it easier to inhale. They were added to cigarettes in the 1950s, in response to the first reports that smoking was hazardous to health. Tobacco companies claimed that their filtered brands had lower tar than others and encouraged consumers to believe that they were safer.

Tobacco smoke is made up of “sidestream smoke” from the burning tip of the cigarette and “mainstream smoke” from the filter or mouth end.

Tobacco smoke contains thousands of different chemicals which are released into the air as particles and gases.

Many toxins are present in higher concentrations in sidestream smoke than in mainstream smoke and, typically, nearly 85% of the smoke in a room results from sidestream smoke.

The particulate phase includes nicotine, “tar” (itself composed of many chemicals), benzene and benzo(a)pyrene. The gas phase includes carbon monoxide, ammonia, dimethylnitrosamine, formaldehyde, hydrogen cyanide and acrolein. Some of these have marked irritant properties and some 60, including benzo(a)pyrene and dimethylnitrosamine, have been shown to cause cancer.

One study has established the link between smoking and lung cancer at the cellular level. It found that a substance in the tar of cigarettes, benzo(a)pyrene diol epoxide (BPDE), damages DNA in a key tumour suppresser gene.

What is Cigarette Tar?

“Tar”, also known as total particulate matter, is inhaled when the smoker draws on a lighted cigarette. In its condensate form, tar is the sticky brown substance (filled with chemicals) which can stain smokers’ fingers and teeth yellow-brown. All cigarettes produce tar but the brands differ in amounts.

The average tar yield of cigarettes has declined from about 30mg per cigarette in the period 1955 to 61 to 11mg today. There have also been reductions in nicotine (from an average of about 2mg in 1955, 61 to about 0.9mg by 1996). Until January 1992, information about tar yields of cigarettes was given in a general fashion on cigarette packets and advertisements as a result of a voluntary agreement between the tobacco industry and the Government.

Due to labeling (Safety) regulations requirements for health warnings on tobacco, cigarette packets must include a statement of both the tar and the nicotine yield per cigarette on the packet itself. The same figures are printed on cigarette advertising, along with the health warning, as part of a voluntary agreement between the industry and health regulators.

Following the discovery in the 1950s that it was the tar in tobacco smoke which was associated with the increased risk of lung cancer, tobacco companies, with the approval of successive governments, embarked on a program to gradually reduce the tar levels in cigarettes.

Although there is a moderate reduction in lung cancer risk associated with lower tar cigarettes, research suggests that the assumed health advantages of switching to lower tar may be largely offset by the tendency of smokers to compensate for the reduction in nicotine (cigarettes lower in tar also tend to be lower in nicotine) by smoking more or inhaling more deeply.

Also, a study by the American Cancer Society found that the use of filtered, lower tar cigarettes may be the cause of adenocarcinoma, a particular kind of lung cancer. There is no evidence that switching to lower tar cigarettes reduces coronary heart disease risk.

Cigarette IngredientsNicotine, an alkaloid, is an extremely powerful drug. The Royal College of Physicians in England and the Surgeon General in USA have affirmed that the way in which nicotine causes addiction is similar to drugs such as heroin and cocaine.

Only 60mg of pure nicotine (contained in two packs of cigarettes) placed on a person’s tongue would kill within minutes.

Nicotine is contained in the moisture of the tobacco leaf: when the cigarette is lit, it evaporates, attaching itself to minute droplets in the tobacco smoke inhaled by the smoker. It is absorbed by the body very quickly, reaching the brain within 7-15 seconds.

It stimulates the central nervous system, increasing the heart beat rate and blood pressure, leading to the heart needing more oxygen. Carbon Monoxide, the main poisonous gas in car exhausts, is present in all cigarette smoke. It binds to haemoglobin much more readily than oxygen, thus causing the blood to carry less oxygen.

Heavy smokers may have the oxygen carrying power of their blood cut by as much as 15%.

Source: Emirates Hospital, Dubai – U.A.E

~CiggyBot

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